Characterizing non-constant relative potency

Characterizing and finding full dimensional efficient facets of PPS with constant returns to scale technology

Relative Potency Estimation in Direct Bioassay with Measurement Errors*

Estimating Relative Potency Based on Multivariate Risk/Benefit Assessment

Relative potency plays a key role in understanding the relationship between the doses of two treatments. Defined as the ratio of equally effective doses, it is central to communicating the relationship between a new drug entering the market and older medications. Because doses are tested and collected at discrete points in clinical trials, estimation in direct assays is hampered by the fact tha...

Fragrances Categorized According to Relative Human Skin Sensitization Potency

BACKGROUND The development of non-animal alternatives for skin sensitization potency prediction is dependent upon the availability of a sufficient dataset whose human potency is well characterized. Previously, establishment of basic categorization criteria for 6 defined potency categories, allowed 131 substances to be allocated into them entirely on the basis of human information. OBJECTIVES ...

Relative potency estimation for synthetic petroleum skin carcinogens.

A procedure for quantitative analysis of skin carcinogenesis data, for the purpose of establishing carcinogenic potency, has been applied to observations obtained from C3H mice exposed continuously to synthetic and natural petroleums. The importance of total polynuclear aromatic (PNA) content to the skin carcinogenic activity of the crude materials was also examined. Of three synthetic petroleu...